ORC1 ->    CDC6
    CLB6 ->    CDC6
    APC1 ->    CLB2
   CDC45 ->    MCM6
    CLB4 ->    ORC1
    BUB1 ->    VHS1
    BUB1 ->    HSL1
    CLB5 ->    ORC1
    BUB1 ->    DUN1
    BUB1 ->    CDC5
   CDC45 ->    CDC5
    YCK1 ->    CLB2
    BUB1 ->    DBF2
    SCC3 ->    DUN1
    MOB1 ->    CLB2
    SCC3 ->    GIN4
    ORC1 ->    CLB5
    SCC3 ->    CDC5
    CDC6 ->    CLB2
    CLB6 ->    ORC1
    CLN1 ->    ORC1
    CLB2 ->    ORC1
    CLB4 ->    CDC6
    SCC3 ->    VHS1
   CDC45 ->    TEM1
    BUB1 ->    SLT2
    YCK1 ->    CLB5
    YCK1 ->    ORC1
    BUB1 ->   RAD53
    CDC6 ->    CLB4
    KIN3 ->    BUB1
    ORC1 ->    CLB6
    YCK1 ->    CLB1
    PDS1 ->    SWE1
    SWE1 ->    BUB1
   DBF20 ->    BUB1
    YCK1 ->    CLN1
    HSL1 ->    BUB1
    MCD1 ->    CLN2
   RAD53 ->    BUB1
    SCC3 ->    SCH9
    CLB1 ->    CDC6
    BUB1 ->   DBF20
    SCC3 ->   RAD53
    ELM1 ->    BUB1
   POL30 ->    SMC1
    CDC6 ->    CLB1
    BUB1 ->    YCK1
    BUB1 ->    GIN4
    ORC1 ->    CLN1
    SCH9 ->    BUB1
    DBF2 ->    BUB1
    BUB1 ->    KIN3
    ORC1 ->    CLB4
    BUB2 ->   CDC47
    CLN1 ->    HSL7
    SWI4 ->    MCD1
    TEM1 ->    CLN1
    BUB1 ->    SCH9
    PCL2 ->    CDC5
    ORC1 ->    CLB2
    YCK1 ->    CDC6
    YCK1 ->    CLB4
    SCC3 ->    PRR1
    CLB2 ->    CDC6
    SCC3 ->    SWE1
    MCD1 ->    BUB1
    SIC1 ->    SCH9
    YCK1 ->    CLB6
    MEC3 ->   DBF20
    SCC3 ->   DBF20
    YCK1 ->    BUB1
    CLN2 ->    PDS1
    SWI4 ->    CLB6
   POL30 ->    CLB5
    ELM1 ->    PCL2
    PCL2 ->   RAD53
    PCL2 ->    SWE1
    PDS1 ->    SLT2
    MCD1 ->   CDC45
    SCC3 ->    DBF2
    CLN2 ->    ELM1
    BUB1 ->    SWE1
    HSL7 ->    CDC5
    SWI4 ->   RAD53
   CDC20 ->   CDC45
    APC1 ->    PRR1
   CDC45 ->    DUN1
    BUB1 ->    PRR1
    DUN1 ->    BUB1
    MOB1 ->    KIN3
    YCK1 ->    SMC3
    SLT2 ->    BUB1
    CLN2 ->    MCD1
    SIC1 ->    PCL2